Abnormal histological findings - Female, 49 - Tissue image [6090730014731541]

This is the histopathological image of CERVIX UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 49Clinical description: Cervical dysplasia, HSILGender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XVIII - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedDiagnosis: Abnormal histological findingsResult of the histopathological examination: Foci of high-grade dysplasia (HSIL / CIN III), located near the transformation zone - IHC: p16 + (block reaction), increased Ki67 index,
present throughout the full thickness of the epithelium. Dysplastic changes do not reach the surgical margin of the endocervix. Features of mature and immature squamous metaplasia and a moderate chronic inflammatory infiltrate.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CERVIX UTERITissue: ExocervixType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存入ZMDL-GUMED的子宫颈（CERVIX UTERI）组织样本的组织病理学图像。样本图像采用奥林巴斯VS200玻片扫描仪采集，放大倍率为20倍，存储格式为DICOM。

患者、样本及诊断的详细信息如下：
患者：年龄49岁；临床描述：宫颈上皮内瘤变、高级别鳞状上皮内病变（HSIL）；性别：女性
诊断分类：ICD-10_10-20；分类编码：第十八章——其他未归类的症状、体征及临床和实验室异常发现
诊断：组织学异常表现
病理检查结果：病灶位于转化区附近的高级别上皮内瘤变（HSIL/CIN III）灶；免疫组化（Immunohistochemistry, IHC）：p16阳性（全层表达），Ki67增殖指数升高，累及上皮全层。异型增生未累及宫颈内口手术切缘。可见成熟及未成熟鳞状上皮化生表现，伴中度慢性炎性浸润。
样本：样本材质：福尔马林固定石蜡包埋（FFPE）；采集方式：手术标本；解剖部位：女性生殖器官；器官：子宫颈（CERVIX UTERI）；组织类型：宫颈外口（Exocervix）；染色类型：HE/阳性染色；染色方式：不适用；抗体：无；技术设备：奥林巴斯VS200；镜头放大倍率：20倍；来源机构：格但斯克医科大学（Medical University Gdańsk）