(A) The previously published pPax8-rtTA plasmid [7] is shown in the top panel. The CreERT2 coding sequence followed by a polyadenylation signal (pA) was used to replace the rtTA sequence of pPax8-rtTA
Data represent the number of animals with NPY ectopic expression in mossy fibers compared to the total number of animals in each group. Note that only Tg2576 mice present aberrant NPY expression. Prop
Genotype composition of the progenies from the crossings of G/R-miRNA and nestin-Cre. The number of the various genotypes was compared with the Mendelian ratio using the Chi Square test to obtain the
The Khakh laboratory developed and characterized a new Aldh1l1-Cre/ERT2 transgenic mouse line to selectively target astrocytes in vivo. Crosses with RiboTag mice allowed sequencing of actively transla
Aldolase C is regarded as the brain-specific form of fructose-1,6-bisphosphate aldolase whereas aldolase A is regarded as muscle-specific. In situ hybridization of mouse central nervous system using i