Expression data from anthrax lethal toxin treated primary cardiomyocytes from 1-3-day-old neonatal Balb/c mice

The activity of known anthrax lethal toxin is insufficient to account the effects on functions of cardiomyocytes. In vivo and in vitro studies showed that Anthrax lethal toxin (LeTx) induce heart damage We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated and down-regulated genes during this process. Primary cardiomyocytes were selected from 1-3-day-old neonatal Balb/c miceat for RNA extraction and hybridization on Affymetrix microarrays. To investigate the mechanism underlying the toxicity of LeTx for cardiomyocytes, we conducted a microarray assay to identify potential genes related to impaired heart function induced by LeTx treatment.