Features and protective efficacy of human monoclonal antibodies targeting M. tuberculosis arabinomannan
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218873
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Human antibody responses to AM/LAM are heterogenous and knowledge of reactivity to specific glycan epitopes at the monoclonal level is limited. Using novel glycan arrays, we characterized a very high affinity monoclonal antibody P1AM25 to AM/LAM, determined this mAb recognized distinct glycan epitopes from other anti-AM/LAM mAbs reported. Monoclonal antibodies at 5 ug/ml were tested for direct binding to 61 synthetic oligosaccharides
创建时间：
2023-11-09
