DROMA datasets(DROMA_DB)

The project main page in mugpeng/DROMA: Drug Response Omics association MAp (DROMA, 卓玛)Input data made from: mugpeng/DROMA_DB: Sqlite db and DromaSet obj for Drug Response Omics association MAp. (DROMA)

Use the database and relavent package from: mugpeng/DROMA_Set: DROMASet is a comprehensive R package for managing and analyzing drug response and omics data across multiple projects. It provides a robust framework for handling complex multi-omics datasets with integrated drug sensitivity information, enabling seamless cross-project comparisons and analyses.

droma.sqlite includes:

project_name

dataset_type

data_types

sample_count

drug_count

created_date

updated_date

CCLE

CellLine

cnv,drug,drug_dose,fusion,meth,mRNA,mutation_gene,mutation_site,proteinms,proteinrppa

1811

24

2025-06-13 10:16:56

2025-06-25 23:18:51

CTRP1

CellLine

drug

241

354

2025-06-13 10:16:56

2025-06-13 10:17:03

CTRP2

CellLine

drug,drug_dose

887

545

2025-06-13 10:16:56

2025-06-24 12:18:53

FIMM

CellLine

drug

50

52

2025-06-13 10:16:56

2025-06-13 10:17:03

GDSC1

CellLine

drug,drug_dose

983

339

2025-06-13 10:16:56

2025-06-23 21:33:47

GDSC2

CellLine

drug,drug_dose

806

188

2025-06-13 10:16:56

2025-06-24 08:23:01

GDSC

CellLine

cnv,mRNA,mutation_gene,mutation_site

1028

0

2025-06-13 10:16:56

2025-06-23 22:10:47

GRAY

CellLine

drug

71

106

2025-06-13 10:16:56

2025-06-13 10:17:03

NCI60

CellLine

drug,mRNA

162

54773

2025-06-13 10:16:56

2025-06-13 10:17:03

PDTXBreast

PDC

drug

37

98

2025-06-13 10:16:56

2025-06-13 10:17:03

Prism

CellLine

drug,drug_dose

521

1442

2025-06-13 10:16:56

2025-06-24 18:43:07

Tavor

PDC

drug,mRNA

53

46

2025-06-13 10:16:56

2025-06-13 10:17:03

UHNBreast

CellLine

drug

57

8

2025-06-13 10:16:56

2025-06-13 10:17:03

UMPDO1

PDO

drug,mRNA,mutation_gene,mutation_site

112

49

2025-06-13 10:16:56

2025-06-21 20:17:39

UMPDO2

PDO

cnv,drug,mRNA,mutation_gene,mutation_site

40

49

2025-06-13 10:16:56

2025-06-21 20:23:05

UMPDO3

PDO

drug,mRNA

42

48

2025-06-13 10:16:56

2025-06-13 10:17:03

Xeva

PDX

cnv,drug,mRNA,mutation_gene

266

38

2025-06-13 10:16:56

2025-06-24 22:02:43

gCSI

CellLine

cnv,drug,drug_dose,mutation_gene

579

44

2025-06-13 10:16:56

2025-06-24 22:20:23

LICOB

PDO

cnv,drug,meth,mRNA,mutation_gene,proteinms

65

76

2025-06-18 15:33:13

2025-06-18 15:46:20

CTRDB

Clinical

mRNA

2745

36

2025-06-23 10:59:04

2025-06-23 10:59:04

HKUPDO

PDO

drug,fusion,mRNA,mutation_gene,mutation_site

69

37

2025-06-23 14:35:49

2025-06-23 14:38:54

For drug metrics, are AAC in 0-1 scale, so that the drug sensitivity are positively correlated with the recorded values.For Xeva(PDX) data, the AAC are calculated by the tumor volume and the details in https://bioconductor.org/packages/release/bioc/vignettes/Xeva/inst/doc/Xeva.pdf Sample projects also include "drug_dose" data type which is the raw data of drug/sample viability information in different dose and used to calculate the AAC or IC50 value.