Crystal structure of human kinesin Eg5 in complex with (R)-fluorastrol
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Crystal structure of human kinesin Eg5 in complex with (R)-fluorastrol Descriptor: (4R)-5-[(S)-(3,4-DIFLUOROPHENYL)(HYDROXY)METHYL]-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-3,4-DIHYDROPYRIMIDINE-2(1H)-THIONE, ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ... Authors: Kaan, H.Y.K, Ulaganathan, V, Rath, O, Laggner, C, Prokopcova, H, Dallinger, D, Kappe, C.O, Kozielski, F. Deposit date: 2010-02-26 Release date: 2010-07-14 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Basis for Inhibition of Eg5 by Dihydropyrimidines: Stereoselectivity of Antimitotic Inhibitors Enastron, Dimethylenastron and Fluorastrol. J.Med.Chem., 53, 2010
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2010-02-26
