Chromosome wide GISTIC results.

A: Amplitude of gains and losses reveal 144 genes of different GISTIC scores across all chromosomes (numbered accordingly). The spikes in the grayed out regions of enrichment correspond to GISTIC scores for genes in these regions. B: Molecular network of genes affected by significant copy number aberrations in tumor samples. These events were located on chromosomes 7, 8, 18 and 20. 11 of 24 genes show no association with the colorectal cancer function. This is in conformation with the GISTIC analysis except for the G-score of TSHZ1. Solid lines between nodes indicate direct molecular interaction between connected genes with respect to CRC. Functions are indicated by shapes: enzymes (diamonds), cytokines (squares), kinases (triangles), transcription factors (horizontal ovals), transmembrane receptors (vertical ovals), transporters (trapezoids), and other (circles).