five

Transcriptome analysis of Yod1 overexpression in a Drosophila Huntington's disease model

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https://www.ncbi.nlm.nih.gov/sra/SRP447293
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In this project we aimed to analyze the transcriptomic consequences of overexpression of the deubiquitinase Yod1 in healthy Drosophila and in a fly model of Huntington's disease. We performed RNA-seq analysis of head samples of 5-day-old female flies carrying the pan-neuronal elav-GAL4 driver alone (control), or overexpressing Httex1.Q120, Yod1, or Httex1.Q120 and Yod1 simultaneously under the influence of elav-GAL4.
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2023-08-02
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