Additional file 1: of Comorbid infections induce progression of visceral leishmaniasis

Figure S1. US hunting dog longitudinal study timeline. Dogs were sampled three times designated by up and down arrows, over a tick season. Peak tick season for all kennel locations is designated by black. The bridge to tick season, dependent on seasonal variation and geographic location, shown in grey. Figure S2. Age and sex distribution of dogs based on tick-borne disease exposure at enrollment. Tick exposure based on SNAPÂŽ 4DxÂŽ Plus Test. a Age distribution. b Sex distribution. Abbreviations: CanL: canine leishmaniosis; qPCR: quantitative polymerase chain reaction; RR: risk ratio; ARR: adjusted risk ratio; OR: odds ratio; CI: confidence interval. (ZIP 212 kb)

补充图S1. 美国狩猎犬纵向研究时间线。本研究在一个蜱虫季内通过上下箭头标记了三次犬只采样节点。所有犬舍所在地的蜱虫活动高峰期以黑色标注；依季节变化与地理位置而异的蜱虫季过渡阶段以灰色标注。
补充图S2. 入组时蜱传疾病暴露情况相关犬只的年龄与性别分布。蜱虫暴露情况依据SNAP® 4Dx® Plus检测试剂盒结果判定。a 年龄分布；b 性别分布。
缩略语：CanL：犬利什曼病（canine leishmaniosis）；qPCR：定量聚合酶链反应（quantitative polymerase chain reaction）；RR：风险比（risk ratio）；ARR：调整后风险比（adjusted risk ratio）；OR：比值比（odds ratio）；CI：置信区间（confidence interval）。（压缩包大小：212 KB）