Cell Health Data Supplementary Files

This dataset contains supplementary files related to the cell-health-data repository that were too large to upload on GitHub. Each of these files were saved to and loaded from an external hard drive during Cell Health Data Processing. These files include:

single_cell_classification_probabilities/ : Single cell classification probabilities derived with each model trained in phenotypic_profiling_model. Each compressed csv file in single_cell_classification_probabilities/ corresponds to single-cell classifications from a particular plate as derived with a particular model. The model used to derive the probabilities is indicated by the file's parent folders. Each compressed csv file includes the metadata (location and perturbation) and phenotypic class probabilities for each cell in the plate.

classification_profiles/ : This folder contains aggregated data known as "classification profiles". These profiles are generated from the single-cell classification probabilities found in the 'single_cell_classification_probabilities/' folder. Specifically, for each model, we find the mean of the single-cell classification probabilities across each perturbation and cell line to create a composite profile. This aggregated data provides a summarized view of cell behavior for each perturbation/cell line combination, as predicted by each model.

For more information regarding the generation of this data, please see cell-health-data/4.classify-single-cell-phenotypes.