Research Platform to Screen and Protect Individuals that Work Within a Food Production, Healthcare, Research or Clinical Organization [RESPECT, study data contributed to the CITF Databank]

<b> Background: </b> During lockdown, frontline workers in the food industry, healthcare and research or clinical organizations were required to work on site where they were at a risk of high exposure to SARS-CoV-2 infections from public interaction. <br>
<b> Aims of the original study: </b> The RESPECT COVID study aimed to 1) determine the asymptomatic transmission of COVID-19 in food production facilities during the pandemic; 2) monitor antibody development and immunity trends over time, and 3) evaluate participants' vaccine uptake and immune responses. <br>
<b>Methods: </b> Employees from various food production facilities in the Greater Toronto Area (GTA) were enrolled in this cohort study regardless of the presence or absence of COVID-19 symptoms. Blood samples were collected at multiple timepoints to understand the longitudinal trend of antibodies induced by infection and vaccination in this population and the influence on COVID-19 transmission. <br>
<b>Summary of the contributed data:</b> The datasets include a total of 5,020 serology samples from 718 participants between January 2020 and December 2021. 508 participants (70%) have linked baseline characteristics data (completed survey). Variables include data in the following areas of information: demographic (age, gender, ethnicity and indigeneity, occupation), general health (symptoms, diseases, previous test, hospitalization), SARS-CoV-2 vaccination and serology.

**背景**：新冠疫情封控期间，食品行业、医疗保健及科研或临床机构的一线工作人员需在岗履职，在此场景下他们因与公众接触，面临极高的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染暴露风险。
**原始研究目标**：RESPECT COVID研究旨在达成三项核心目标：1）明确疫情期间食品生产场所内新型冠状病毒肺炎（COVID-19）的无症状传播特征；2）动态监测抗体演化与免疫趋势的长期变化；3）评估参与者的疫苗接种率及其免疫应答水平。
**研究方法**：本队列研究纳入了大多伦多地区（Greater Toronto Area, GTA）多家食品生产工厂的员工，无论其是否出现新型冠状病毒肺炎相关症状。研究人员在多个时间节点采集血液样本，以解析该人群中感染与疫苗接种诱导的抗体纵向变化趋势，以及其对新型冠状病毒肺炎传播的影响。
**贡献数据概要**：本数据集涵盖2020年1月至2021年12月期间，718名参与者共计5020份血清学（serology）样本。其中508名参与者（占比70%）配套有基线特征数据（即完成的调查问卷）。数据集变量涵盖以下几类信息：人口统计学资料（年龄、性别、族裔、原住民身份与职业）、一般健康状况（症状、疾病史、既往检测与住院情况）、SARS-CoV-2疫苗接种情况及血清学检测结果。