Guy's Breast Cancer Lymph Nodes (GRAPE)

This is a retrospective dataset of 1523 H&E-stained whole slide images (WSI) of lymph nodes from breast cancer patients. The cohort consisted of 177 patients (122 LN-positive - metastasis was reported in at least 1 LN - and 55 LN-negative patients) with invasive breast carcinoma treated between 1984 and 2002 at Guy’s Hospital London, UK. Slides were scanned and digitised at 40x magnification (0.23 µm/pixel), NanoZoomer H.T2.0 2.0-HT (Hamamatsu Photonics UK, Ltd, Welwyn Garden City, UK). WSIs are in .ndpi format.

本数据集为回顾性队列数据集，涵盖1523张乳腺癌患者淋巴结的苏木精-伊红（Hematoxylin and Eosin, H&E）染色全视野数字切片（Whole Slide Image, WSI）。该队列共纳入177例浸润性乳腺癌患者，均于1984年至2002年间在英国伦敦盖伊医院接受治疗，其中122例为淋巴结阳性（Lymph Node-positive, LN-positive，即至少1枚淋巴结检出肿瘤转移），55例为淋巴结阴性（Lymph Node-negative, LN-negative）。所有切片均采用英国韦尔温花园城滨松光子学英国有限公司（Hamamatsu Photonics UK, Ltd）的NanoZoomer H.T2.0 2.0-HT扫描仪，以40倍放大倍率（0.23 µm/像素）完成扫描与数字化处理。所有全视野数字切片均采用.ndpi格式存储。