NHLBI TOPMed: Women's Health Initiative (WHI)

This is Whole Genome Sequencing data from the TOPMed participation of the Women's Health Initiative. Approximately 11,100 subjects were involved in this study: approximately 1,100 cases of VTE, 4,000 cases of ischemic stroke, 900 cases of hemorrhagic stroke, and 5,100 controls. Summary level phenotypes for the WHI Cohort study participants can be viewed at the top-level study page phs000200 WHI Cohort. Individual level phenotype data and molecular data for all WHI top-level study and substudies are available by requesting Authorized Access to the WHI Cohort study [phs000200](./study.cgi?study_id=phs000200).

本数据集为妇女健康倡议（Women's Health Initiative, WHI）参与精准医学跨组学计划（Trans-Omics for Precision Medicine, TOPMed）所产生的全基因组测序（Whole Genome Sequencing）数据。本研究共纳入约11100名受试者，其中包含约1100例静脉血栓栓塞症（Venous Thromboembolism, VTE）病例、4000例缺血性脑卒中病例、900例出血性脑卒中病例，以及5100例对照个体。WHI队列研究参与者的汇总级表型数据可在顶级研究页面phs000200 WHI Cohort进行查看。所有WHI顶级研究及子研究的个体级表型数据与分子数据，需通过申请获得WHI队列研究[phs000200](./study.cgi?study_id=phs000200)的授权访问权限后方可获取。