Additional file 20 of Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes

Additional file 20: Table S16. Summary statistics of the single clone association analysis with clinical phenotypes in rheumatoid arthritis. The statistical significance of the association between each single clone and response to TNFi therapy, disease activity, RF and ACPA phenotypes is shown at the chain level. For each clone, the statistical significance determined by the Hurdle, continuous and discrete models is provided. Abbreviations: FDR, false discovery rate.

附加文件20：表S16。类风湿关节炎患者单一克隆与临床表型关联分析的汇总统计结果。各单一克隆与肿瘤坏死因子抑制剂（TNFi）治疗应答、疾病活动度、类风湿因子（RF）及抗瓜氨酸化蛋白抗体（ACPA）表型之间的关联统计学显著性，均以链级水平呈现。针对每个克隆，均提供了基于Hurdle模型、连续模型与离散模型计算得到的统计学显著性结果。缩略词说明：FDR，错误发现率（false discovery rate）。