TRPC6 variants in patients with iMN (n = 101).

Chr = chromosome; position = basepair position based on UCSC genome browser version Human Feb. 2009 (GRCh37/hg19) assembly; name = rs identifier; ref = genomic reference allele; all = alleles; CEU AF = allele frequencies variant allele in control population. Control population consists of Caucasian population from 1000 Genomes project (release 10 - March 2012), complemented with data form 292 geographically matched controls for variants marked with **; ∧ = not reported in 1000 Genomes project; AF patient = patient minor allele frequencies; p-value = comparison allele frequencies controls and patients; AF PLA2R = minor allele frequencies in PLA2R positive patients (n = 62); p-value* = comparison allele frequencies controls and PLA2R positive patients; genomic level = NC_000002.11; ref cDNA = reference allele cDNA (given that TRPC6 is on the negative strand); cDNA = NM_004621.5; prot. level = NP_004612.2; CCD = coiled-coiled domain; TMD = transmembrane domain.