TEAD1 in complex with a reversible inhibitor N-[(1S)-2-hydroxy-1-(1-methyl-1H-pyrazol-3-yl)ethyl]-2-methyl-8-[4-(trifluoromethyl)phenyl]-2H,8H-pyrazolo[3,4-b]indole-5-carboxamide
收藏Protein Data Bank Japan2025-04-09 更新2026-04-19 收录
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TEAD1 in complex with a reversible inhibitor N-[(1S)-2-hydroxy-1-(1-methyl-1H-pyrazol-3-yl)ethyl]-2-methyl-8-[4-(trifluoromethyl)phenyl]-2H,8H-pyrazolo[3,4-b]indole-5-carboxamide Descriptor: 2-methyl-~{N}-[(1~{S})-1-(1-methylpyrazol-3-yl)-2-oxidanyl-ethyl]-4-[4-(trifluoromethyl)phenyl]pyrazolo[3,4-b]indole-7-carboxamide, GLYCEROL, SULFATE ION, ... Authors: Musil, D, Freire, F. Deposit date: 2024-07-29 Release date: 2025-01-22 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (1.93 Å) Cite: MoA Studies of the TEAD P-Site Binding Ligand MSC-4106 and Its Optimization to TEAD1-Selective Amide M3686. J.Med.Chem., 68, 2025
创建时间：
2024-07-29
