The evolution of antibiotic resistance islands occurs within the framework of plasmid lineages

Supplementary data for "The agglomeration of antibiotic resistance genes in resistance islands is biased towards specific large plasmid lineages".This folder contains the data of collinear syntenic blocks (CSBs) in the analysis of plasmid resistance islands in 2,441 genomes from Escherichia, Salmonella, and Klebsiella.1. csb.amr.ins0.q4.csb: CSB result file calculated using CSBFinder-S2. info.csb.amr.fasta: Orthology information file of gene families as an optional input file for CSBFinder-S3. csb.data.tsv: Gene content table for retrieving CSB sequence from the genomes in RefSeq database.4. GuideVideo: In this video, I show an example of how to use CSBFinder-S to explore CSB data for resistance island analysis.

本数据集为《耐药岛中抗生素抗性基因的聚集倾向于特定大型质粒谱系》一文的补充数据。本文件夹包含针对埃希菌属、沙门氏菌属和克雷伯菌属共2441个基因组的质粒耐药岛分析中所涉及的共线性同源区块（collinear syntenic blocks, CSBs）数据。
1. csb.amr.ins0.q4.csb：采用CSBFinder-S计算得到的共线性同源区块结果文件
2. info.csb.amr.fasta：基因家族直系同源信息文件，为CSBFinder-S的可选输入文件
3. csb.data.tsv：用于从RefSeq数据库的基因组中检索共线性同源区块序列的基因含量表
4. 操作指南视频：本视频演示了如何使用CSBFinder-S探索共线性同源区块数据以开展耐药岛分析的示例。