Expression of synovial phenotypic and vascular markers in patients who fulfilled 2010 ACR/EULAR criteria for RA at baseline subclassified according to fulfillment of 1987 ACR criteria at baseline and after follow up.

Values are presented as median (interquartile range). A Kruskal-Wallis test was used to compare the different diagnostic groups; a P-value of <0.05 was considered statistically significant. RA = rheumatoid arthritis. UA = undifferentiated arthritis. CD3 refers to T cells; CD55– fibroblast-like synoviocytes; CD68– macrophages; CD22– B cells; CD138– plasma cells; tryptase – mast cells. L = intimal lining layer; SL = synovial sublining; vWF = von Willebrand factor; VEGF = vascular endothelial growth factor; VCAM-1 = vascular cell adhesion molecule-1. IOD = integrated optical density.