We used an inducible shRNA system and RNA-Seq to examine gene expression changes in acute myeloid leukemia THP1 cells following silencing of RUVBL2. RUVBL2 is a AAA+ ATPase that functions in a number
This project investigates the genomic and immunogenetic landscape of extramedullary acute myeloid leukemia (AML), a rare and poorly understood manifestation of AML that occurs outside the bone marrow.
We performed genome-wide copy number analysis with paired normal and tumor DNA obtained from 86 adult patients with de novo AML using the Affymetrix Genome-Wide Human SNP array 6.0 containing 1.85 mil
