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Crystal structure of Zika Virus NS2B-NS3 protease in complex with compound 1

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Protein Data Bank Japan2026-02-25 更新2026-04-19 收录
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Crystal structure of Zika Virus NS2B-NS3 protease in complex with compound 1 Descriptor: (1~{E})-1-[3-[(2~{R})-1-phenylpropan-2-yl]-2~{H}-1,2,3-oxadiazol-3-ium-5-ylidene]-3-[3-(trifluoromethyl)phenyl]urea, Genome polyprotein, ISOPROPYL ALCOHOL, ... Authors: Ontoria, J.M, Torrente, E. Deposit date: 2025-12-18 Release date: 2026-01-28 Last modified: 2026-02-25 Method: X-RAY DIFFRACTION (2.48 Å) Cite: An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models. Nat Commun, 17, 2026
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2025-12-18
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