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Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

NCATS Open Data2021-03-25 更新2026-08-08 收录

抗病毒药物研发

新冠病毒变异株耐药性

数据链接：

https://doi.org/10.1101/2021.01.24.427991 数据链接链接失效反馈

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Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

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创建时间：

2021-02-04

药物发现

抗病毒药物研发

Few Zika virus (ZIKV) outbreaks had been reported since its first detection in 1947, until the recent epidemics occurred in South America (2014/2015) and expeditiously became a global public health em

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a broad range of SARS-CoV-2 inhibitor. Title: A siRNA targets and inhibits a broad range of SARS-CoV-2 infections including Delta variant

抗病毒药物研发

RNA干扰治疗

The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants has altered the trajectory of the COVID-19 pandemic and raised some uncertainty on long term efficiency of vaccin

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Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z1530724813

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蛋白质晶体结构解析

Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z1530724813 Descriptor: 2-(3-chlorophenyl)-N-(isoquinolin-4-yl)acetamide, 3C-like proteinase Authors: Kovalevsky,

Protein Data Bank Japan2023-10-18 更新40

Identification of a potential anti-viral drug targeting allosteric site of papain-like protease against rubella using a molecular modeling approach

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分子建模

Rubella virus (RUBV) is responsible for causing rashes, lymphadenopathy, and fever which are the hallmarks of an acute viral illness called Rubella. For RUBV replication, the non-structural polyprotei

DataCite Commons2026-03-02 更新60

Data_Sheet_2_Discovery of Retro-1 Analogs Exhibiting Enhanced Anti-vaccinia Virus Activity.pdf

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正痘病毒

Orthopoxviruses (OPXVs) are an increasing threat to human health due to the growing population of OPXV-naive individuals after the discontinuation of routine smallpox vaccination. Antiviral drugs that

NIAID Data Ecosystem40

Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant

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