Expression data from aged wild-type, met15_ and rtg3_ met15_ yeast

To explore putative connections between genetic methionine restriction and the retrograde response, we asked whether the altered transcriptional program of methionine-restricted cells required RTG3 (which is indispensible for retrograde signaling in yeast).为探究遗传性甲硫氨酸限制与逆行反应之间的潜在关联，我们考察了甲硫氨酸限制细胞的转录程序改变是否依赖RTG3——该基因对于酵母中的逆行信号传导不可或缺。