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Characterisation of HMGB1 interactome in PNT2 prostate cells

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https://www.omicsdi.org/dataset/pride/PXD007867
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资源简介:
HMGB1 and HMGB2 are members of the High Mobility Group (HMG) protein superfamily that contain a DNA binding domain (HMG-Box), and their overexpression has been related to main cancer hallmarks, tumor progression, metastasis formation and bad prognosis. We have used yeast two hybrid and affinity purification-mass spectrometry to explore HMGB1 and HMGB2 protein interactions in prostate and ovarian epithelial cells.
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2018-05-07
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