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Human GPX4 in complex with covalent Inhibitor ML162 (S enantiomer)

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Protein Data Bank Japan2025-10-01 更新2026-03-21 收录
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Human GPX4 in complex with covalent Inhibitor ML162 (S enantiomer) Descriptor: (2~{S})-2-[2-chloranylethanoyl-(3-chloranyl-4-methoxy-phenyl)amino]-~{N}-(2-phenylethyl)-2-thiophen-2-yl-ethanamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... Authors: Hillig, R.C, Moosmayer, D, Hilpmann, A, Hoffmann, L, Schnirch, L, Eaton, J.K, Badock, V, Gradl, S. Deposit date: 2018-09-07 Release date: 2020-04-01 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162. Acta Crystallogr D Struct Biol, 77, 2021
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2018-09-07
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