Tuberculosis (TB) causes an estimated 2 million people per year globally. However, despite technological advances of the 21st century, there are no efficacious vaccines that prevent TB transmission. T
BackgroundAntigen specific release of IP-10 is the most promising alternative marker to IFN-γ for infection with M. tuberculosis. Compared to Interferon-γ release assays (IGRA), IP-10 is released in h
A blood transcriptome analysis was performed on a set of healthy subjects and patients infected with M. africanum (MAF) or M. tuberculosis (MTB). All study participants were recruited from Mali. Overa
Although vitamin D deficiency is a common feature among patients presenting with active tuberculosis, the full scope of vitamin D action during Mycobacterium tuberculosis (Mtb) infection is poorly und