Longitudinal fMRI dataset for pain modulation through learning descending pain inhibition through positive imagery and RIII reflex biofeedback

The aim of the study was to determine which brain areas are preferentially activated when healthy participants learned to activate their descending pain inhibition via a cognitive strategy. We compared participants brain activity with fMRI before and after learning a cognitive strategy via RIII-biofeedback-training. This experiment was a longitudinal MRI study with two MRI scans: MRI1: pre-intervention and MRI2: post-intervention. Intervention was a previously published feedback training (see doi:10:1002/ejp.570) to teach participants a cognitive strategy to reduce their spinal nociception.

本研究旨在明确健康受试者通过认知策略激活下行性疼痛抑制时，优先激活的脑区。我们采用功能磁共振成像（fMRI），对比了受试者在通过RIII生物反馈训练学习认知策略前后的脑活动情况。本实验为一项纵向磁共振成像研究，包含两次磁共振扫描：干预前扫描（MRI1）与干预后扫描（MRI2）。本次干预采用已发表的反馈训练方案（详见doi:10:1002/ejp.570），用于指导受试者掌握可降低脊髓伤害性感受的认知策略。