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Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies

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Organisation for Economic Co-operation and Development2026-02-07 收录
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https://www.oecd.org/en/publications/test-no-453-combined-chronic-toxicity-carcinogenicity-studies_9789264071223-en.html
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The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...
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