Gene expression changes throughout MMTV-PyMT cell aggregation into clusters
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA648151
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资源简介：
To identify metastasis-promoting signals generated by aggregation, we first developed an experimental system to temporally control cluster formation and monitor downstream molecular events. When MMTV-PyMT tumor organoids were enzymatically dissociated and cultured in suspension, individual tumor cells spontaneously assembled into loosely attached cell aggregates by 6 hrs and more compact clusters by 24 hrs. RNA-sequencing revealed changes in gene expression as cells organized into clusters.
创建时间：
2020-07-23
