Bilayer Effects of Antimalarial Compounds
收藏Figshare2016-01-15 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Bilayer_Effects_of_Antimalarial_Compounds_/1597757
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Because of the perpetual development of resistance to current therapies for malaria, the Medicines for Malaria Venture developed the Malaria Box to facilitate the drug development process. We tested the 80 most potent compounds from the box for bilayer-mediated effects on membrane protein conformational changes (a measure of likely toxicity) in a gramicidin-based stopped flow fluorescence assay. Among the Malaria Box compounds tested, four compounds altered membrane properties (p
创建时间：
2016-01-15
