Summary of Adverse Events.

†Total adverse events encompasses all intensities. Mild = no interference with daily activities; moderate = interferes with daily activities; severe = daily activities interrupted.*Subjects with multiple symptoms were counted in all applicable symptom categories.‡In skin surrounding the index lesion.Localized infections generally occurred at the biopsy site, although a causal relationship to the biopsy was not established.§One subject suffered from pre-existing anemia and cardiac arrhythmia.Mild, clinically insignificant elevations in serum creatinine were noted in both subjects at day 10 and resolved by day 20.