Organocatalytic One-Pot Asymmetric Synthesis of Thiolated Spiro-γ-lactam Oxindoles Bearing Three Stereocenters
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https://figshare.com/articles/dataset/Organocatalytic_One-Pot_Asymmetric_Synthesis_of_Thiolated_Spiro-_-lactam_Oxindoles_Bearing_Three_Stereocenters/3436832
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资源简介：
The first asymmetric synthesis of spiro-γ-lactam oxindoles bearing three stereocenters is reported. One-pot thiol-Michael/Mannich/lactamization reactions promoted by a recyclable fluorous bifunctional cinchona alkaloid/thiourea organocatalyst afford products in moderate to good yields with up to 95% ee and 6:1 dr.
创建时间：
2016-06-27
