Supporting data for "Twelve years of SAMtools and BCFtools"

SAMtools and BCFtools are widely used programs for processing and analysing high-throughput sequencing data. They include tools for file format conversion and manipulation, sorting, querying, statistics, variant calling and effect analysis amongst other methods. The first version appeared online twelve years ago and has been maintained and further developed ever since, with many new features and improvements added over the years. The SAMtools and BCFtools packages represent a unique collection of tools that have been used in numerous other software projects and countless genomic pipelines. Both SAMtools and BCFtools are freely available on GitHub under the permissive MIT licence, free for both non-commercial and commercial use. Both packages have been installed over a million times via Bioconda. The source code and documentation are available from https://www.htslib.org.

SAMtools与BCFtools是两款应用广泛的高通量测序数据处理与分析程序。它们涵盖文件格式转换与操作、排序、查询、统计、变异检测及效应分析等多种分析工具。该工具集的首个版本于十二年前上线发布，此后一直得到持续维护与迭代更新，多年来新增了诸多功能并完成了多项优化。SAMtools与BCFtools工具包构成了一套独一无二的工具集合，已被众多其他软件项目与海量基因组分析流程所采用。两款工具均以宽松的MIT许可证（MIT License）形式在GitHub平台开源，可免费用于非商业与商业场景。两款工具包通过Bioconda的安装总量已超百万次。其源代码与官方文档可从https://www.htslib.org获取。