Data from: Diversity of bat astroviruses in Lao PDR and Cambodia

Astroviruses are known to infect humans and a wide range of animal
species, and can cause gastroenteritis in their hosts. Recent studies have
reported astroviruses in bats in Europe and in several locations in China.
We sampled 1876 bats from 17 genera at 45 sites from 14 and 13 provinces
in Cambodia and Lao PDR respectively, and tested them for astroviruses.
Our study revealed a high diversity of astroviruses among various
Yangochiroptera and Yinpterochiroptera bats. Evidence for varying degrees
of host restriction for astroviruses in bats was found. Furthermore,
additional Pteropodid hosts were detected. The astroviruses formed
distinct phylogenetic clusters within the genus Mamastrovirus, most
closely related to other known bat astroviruses. The astrovirus sequences
were found to be highly saturated indicating that phylogenetic
relationships should be interpreted carefully. An astrovirus clustering in
a group with other viruses from diverse hosts, including from ungulates
and porcupines, was found in a Rousettus bat. These findings suggest that
diverse astroviruses can be found in many species of mammals, including
bats.

星状病毒（Astrovirus）已知可感染人类及多种动物宿主，并可引发宿主罹患胃肠炎。近期已有研究在欧洲以及中国多个地区的蝙蝠样本中检出星状病毒。本研究分别从柬埔寨的14个省份、老挝人民民主共和国（Lao PDR）的13个省份的45个采样点中，采集了隶属于17个属的1876份蝙蝠样本，并对其开展星状病毒检测。本研究揭示了阳翼手亚目（Yangochiroptera）与阴翼手亚目（Yinpterochiroptera）各类蝙蝠中星状病毒的高度多样性。研究发现蝙蝠星状病毒存在不同程度的宿主限制性特征。此外，本研究还检出了额外的狐蝠科（Pteropodidae）宿主。星状病毒在哺乳动物星状病毒属（Mamastrovirus）内形成了独立的系统发育簇，与其他已知蝙蝠星状病毒的亲缘关系最为密切。分析显示，本次获得的星状病毒序列已呈现高度饱和状态，提示对其系统发育关系的解读需谨慎。在一只果蝠属（Rousettus）蝙蝠样本中，发现一株星状病毒与来自有蹄类动物、豪猪等多种宿主的病毒聚为一类。上述研究结果表明，包括蝙蝠在内的诸多哺乳动物类群中均可检出多样化的星状病毒。