Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer
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Crystal structure of the methyltransferase domain of R882H/N879A DNMT3A homotetramer Descriptor: DNA (cytosine-5)-methyltransferase 3A, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE Authors: Lu, J.W, Song, J.K. Deposit date: 2023-07-05 Release date: 2024-03-13 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations. Nat Commun, 15, 2024
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2023-07-05
