Comparative Genomic Hybridization in traditional fermentative Saccharomyces cerevisiae yeasts

We study the genetics, including microarray karyotyping using comparative genomic hybridization to explore global changes in the genomic DNA, of four S. bayanus var uvarum strains related to traditional fermentations of very different sources comparing to the sequenced S. cerevisiae laboratory strain (S288C)本研究以已完成测序的酿酒酵母（S. cerevisiae）实验室菌株S288C为参照，对四株来源各异且关联传统发酵过程的贝氏酵母葡萄变种（S. bayanus var uvarum）菌株开展遗传学研究，研究内容涵盖采用比较基因组杂交（comparative genomic hybridization）技术进行微阵列核型分析，以探究其基因组DNA的全局变化。