Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP102, a multitargeted kinase inhibitor
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Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP102, a multitargeted kinase inhibitor Descriptor: 1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src Authors: Blair, J.A, Apsel, B, Knight, Z.A, Shokat, K.M. Deposit date: 2008-09-25 Release date: 2008-10-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat.Chem.Biol., 4, 2008
创建时间:
2008-09-25



