comparative RNA-seq analysis of murine lung infected with A.fumigatus. comparative RNA-seq analysis of murine lung infected with A.fumigatus

We report the application of RNA-seq analysis for high-throughput profiling of murine lungs infected with Aspergillus fumigatus. We compared the lung transcription of wildtype murine lungs and lungs from mice deficient in metabolic cytokine adiponectin. Overall design: Examination of 2 different mice strain and comparison of lung transcripts in response to Aspergillus fumigatus infection.

搜集汇总

背景与挑战

背景概述

该数据集包含对感染烟曲霉的小鼠肺部进行的比较RNA-seq分析，旨在研究野生型小鼠与缺乏代谢细胞因子脂联素的小鼠在感染后的肺部转录组差异。数据包括6个SRA实验和1个GEO数据集，共6个生物样本，为研究脂联素在侵袭性曲霉病中抑制炎症性肺部病理的作用提供了转录组证据。