Crystal structure of human RXRalpha ligand binding domain complexed with CBTF-EE.
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of human RXRalpha ligand binding domain complexed with CBTF-EE. Descriptor: 1-[3-(2-ethoxyethoxy)-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl]-2-(trifluoromethyl)benzimidazole-5-carboxylic acid, GLYCEROL, Retinoic acid receptor RXR-alpha Authors: Watanabe, M, Fujihara, M, Motoyama, T, Kawasaki, M, Yamada, S, Takamura, Y, Ito, S, Makishima, M, Nakano, S, Kakuta, H. Deposit date: 2020-06-27 Release date: 2021-01-06 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Discovery of a "Gatekeeper" Antagonist that Blocks Entry Pathway to Retinoid X Receptors (RXRs) without Allosteric Ligand Inhibition in Permissive RXR Heterodimers. J.Med.Chem., 64, 2021
创建时间：
2020-06-27
