Analysis of metabolic abnormalities and risk factors in people of different age groups

Objective To explore the metabolic abnormalities in people of different age groups and analyze the risk factors of metabolic abnormalities syndrome.Methods A total of 4500 people who underwent physical examinations in our hospital were selected as the research subjects and divided into 6 groups according to different age groups. A questionnaire survey was conducted on the personal data of the subjects, and physical (height, weight, waist circumference, blood pressure) and biochemical indicators (blood lipids, blood sugar) were tested. The levels of metabolic indicators and the prevalence of hypertension, hyperlipidemia, hyperglycemia, and metabolic syndrome in people of different age groups were compared, and logistic regression was used to analyze the risk factors for metabolic syndrome.Results The detection rates of hypertension, hyperlipidemia, hyperglycemia and metabolic syndrome in the total population were 22.02%, 34.48%, 6.20% and 20.22% respectively. There were significant differences in body mass index, diastolic blood pressure, systolic blood pressure, total cholesterol, triacylglycerol, fasting blood glucose, and 2-h postprandial blood glucose levels among people of different age groups (P<0.05). The detection rates of hypertension, hyperlipidemia, hyperglycemia, and metabolic syndrome increase with age, and there are significant differences in each age group (P<0.05). T There were significant differences in the detection rates of hypertension, hyperlipidemia, and metabolic syndrome among subjects of different genders (P<0.05). Among those aged ≥55 years old, the prevalence of hypertension exceeds 50%, and among this age group, female subjects have a higher detection rate of hyperlipidemia. The detection rate of metabolic syndrome in men in the two age groups of 26-35 and 36-45 is significantly higher than that in women (P<0.05), while the detection rate of metabolic syndrome in women aged 56-65 is significantly higher than men (P<0.05). Logistic regression analysis showed that gender, age, economic income, high-fat diet, leisure physical activity, smoking, family history of diabetes, and family history of hypertension are all independent risk factors for the occurrence of metabolic syndrome.Conclusion With the increase of age, the detection rate of metabolic abnormalities such as hypertension, hyperlipidemia, hyperglycemia and metabolic syndrome is increasing, and the detection rate in men is higher than that in women. The occurrence of metabolic syndrome is getting younger, especially in men, and the middle-aged and elderly are the high-incidence age group of metabolic syndrome. Gender, age, economic income, high-fat diet, leisure physical activities, smoking, family history of diabetes, and family history of hypertension are closely related to the occurrence of metabolic syndrome.

研究目的：探讨不同年龄人群的代谢异常情况，分析代谢综合征（Metabolic Syndrome）的危险因素。方法：选取我院4500名体检人群作为研究对象，按年龄分组划分为6个组别。对研究对象开展个人信息问卷调查，并进行体格检查（身高、体重、腰围、血压）与生化指标检测（血脂、血糖）。比较不同年龄人群的代谢指标水平及高血压、高脂血症、高血糖症与代谢综合征的患病率；采用Logistic回归分析代谢综合征的危险因素。结果：总体人群中高血压、高脂血症、高血糖症及代谢综合征的检出率分别为22.02%、34.48%、6.20%及20.22%。不同年龄人群的体质指数、舒张压、收缩压、总胆固醇、三酰甘油、空腹血糖及餐后2小时血糖水平均存在显著差异（P<0.05）。高血压、高脂血症、高血糖症及代谢综合征的检出率随年龄增长而升高，各年龄组间差异均具有统计学意义（P<0.05）。不同性别受试者的高血压、高脂血症及代谢综合征检出率存在显著差异（P<0.05）。在年龄≥55岁的人群中，高血压患病率超过50%；该年龄段女性受试者的高脂血症检出率更高。26~35岁、36~45岁两个年龄段的男性代谢综合征检出率显著高于女性（P<0.05），而56~65岁年龄段女性的代谢综合征检出率显著高于男性（P<0.05）。Logistic回归分析显示，性别、年龄、经济收入、高脂饮食、闲暇体力活动、吸烟、糖尿病家族史及高血压家族史均为代谢综合征发生的独立危险因素。结论：随着年龄增长，高血压、高脂血症、高血糖症及代谢综合征等代谢异常的检出率逐渐升高，且男性检出率高于女性。代谢综合征的发生呈年轻化趋势，尤以男性为甚，中老年人群为代谢综合征的高发年龄段。性别、年龄、经济收入、高脂饮食、闲暇体力活动、吸烟、糖尿病家族史及高血压家族史均与代谢综合征的发生密切相关。