Supplementary Material for: Long-Term Mechanical Ventilation: Recommendations of the Swiss Society of Pulmonology

Long-term mechanical ventilation is a well-established treatment for chronic hypercapnic respiratory failure (CHRF). It is aimed at improving CHRF-related symptoms, health-related quality of life, survival, and decreasing hospital admissions. In Switzerland, long-term mechanical ventilation has been increasingly used since the 1980s in hospital and home care settings. Over the years, its application has considerably expanded with accumulating evidence of beneficial effects in a broad range of conditions associated with CHRF. Most frequent indications for long-term mechanical ventilation are chronic obstructive pulmonary disease, obesity hypoventilation syndrome, neuromuscular and chest wall diseases. In the current consensus document, the Special Interest Group of the Swiss Society of Pulmonology reviews the most recent scientific literature on long-term mechanical ventilation and provides recommendations adapted to the particular setting of the Swiss healthcare system with a focus on the practice of non-invasive and invasive home ventilation in adults.

长期机械通气（long-term mechanical ventilation）是慢性高碳酸血症性呼吸衰竭（chronic hypercapnic respiratory failure, CHRF）的成熟治疗方案，旨在改善CHRF相关临床症状、提升健康相关生活质量、延长患者生存期，并降低住院率。自20世纪80年代以来，长期机械通气在瑞士的医院及居家照护场景中的应用持续增长。多年来，随着针对多种与CHRF相关病症的有益疗效证据不断积累，其应用范围已显著拓展。长期机械通气最常见的适应证包括慢性阻塞性肺疾病、肥胖低通气综合征、神经肌肉疾病及胸壁疾病。在本共识文件中，瑞士胸科学会（Swiss Society of Pulmonology）专项兴趣小组梳理了长期机械通气领域的最新科学文献，并结合瑞士医疗体系的特定场景制定了针对性推荐意见，重点关注成人无创与有创居家通气的临床实践。