Dataset for "Nanocrystallites Modulate Intermolecular Interactions in Cryoprotected Protein Solutions"

1. "fig_1a.csv": Small-angle scattering intensity I(Q) as a function of the momentum transfer Q measured for 10 mg/ml lysozyme in 23 mol% glycerol-water at different temperatures upon cooling down after subtracting the scattering intensity measured on the pure solvent. (Note: I(Q) in arbitrary units). 2. "fig_1_inset.csv": Radii of gyration as a function of temperature upon cooling and warming as extracted from fitting the I(q)s for the dilute sample with an elliptical form factor. 3. "fig_1b.csv": Small-angle scattering intensity I(Q) as a function of the momentum transfer Q measured for 200 mg/ml lysozyme in 23 mol% glycerol-water at different temperatures upon cooling down after subtracting the scattering intensity measured on the pure solvent. (Note: I(Q) in arbitrary units). 4. "fig_2a.csv": Wide-angle scattering intensity I(Q) as a function of the momentum transfer Q measured for 200 mg/ml lysozyme in 23 mol% glycerol-water for different temperatures upon cooling. (Note: I(Q) in arbitrary units). 5. "fig_2b.csv": Wide-angle scattering intensity I(Q) as a function of the momentum transfer Q measured for 200 mg/ml lysozyme in 23 mol% glycerol-water for different temperatures upon warming up. (Note: I(Q) in arbitrary units). 6. "fig_2c.csv": 2D scattering pattern in the vicinity of Q ≈ 16-20 nm^-1 measured at T = 197 K during heating. 7. "fig_2d.csv": 2D scattering pattern in the vicinity of Q ≈ 16-20 nm^-1 measured at T = 245 K during heating. 8. "fig_2e.csv": Temperature evolution of the I(Q) around the ice Ih[002] diffraction peak centered at Q ≈ 17 nm⁻¹ upon cooling. 9. "fig_2f.csv": Temperature evolution of the I(Q) around the ice Ih[002] diffraction peak centered at Q ≈ 17 nm⁻¹ upon warming up. 10. "fig_3a.csv": Temperature dependence of the Q-value of the SAXS I(Q) peak position for a 200 mg/ml lysozyme in glycerol-water solution during a deep temperature cycle down to 195 K. 11. "fig_3b.csv": Temperature dependence of the Q-value of the SAXS I(Q) peak position for a 200 mg/ml lysozyme in glycerol-water solution during a medium temperature cycle down to 225 K. 12. "fig_3c.csv": Temperature dependence of the Q-value of the SAXS I(Q) peak position for a 200 mg/ml lysozyme in glycerol-water solution during a shallow temperature cycle down to 245 K. 13. "fig_3d.csv": Temperature dependence of the Q-value of the WAXS I(Q) peak position for a 200 mg/ml lysozyme in glycerol-water solution during a deep temperature cycle down to 195 K. 14. "fig_3e.csv": Temperature dependence of the Q-value of the WAXS I(Q) peak position for a 200 mg/ml lysozyme in glycerol-water solution during a medium temperature cycle down to 225 K. 15. "fig_3f.csv": Temperature dependence of the Q-value of the WAXS I(Q) peak position for a 200 mg/ml lysozyme in glycerol-water solution during a shallow temperature cycle down to 245 K 16. "fig_4a.csv": The protein-protein structure factor S(Q) at different temperatures (T = 195-300 K) upon cooling obtained from the fits using the two-Yukawa model. 17. "fig_4b.csv": Temperature dependence of the attraction strength parameter K₁ (in units of k_bT) extracted from fitting the SAXS curves upon cooling down and warming up. 18. "fig_4c.csv": The two-Yukawa potential at different temperatures (T = 195-300 K) upon cooling down. 19. "fig_4d.csv": The pair distribution function g(r) at different temperatures (T = 195-300 K) derived from the modeled structure factors. Additionally, a Jupyter notebook "open-data.ipynb" which shows how to load and plot the data from the csv files in Python. <br> <br> <br> <br> <br> <br>

1. "fig_1a.csv": 记录了23 mol%甘油-水体系中浓度为10 mg/ml的溶菌酶样品，在降温过程中不同温度下测得的小角散射强度I(Q)随动量转移Q的变化关系，数据已扣除纯溶剂的散射本底。注：I(Q)单位为任意单位。
2. "fig_1_inset.csv": 通过采用椭球形状因子（elliptical form factor）对稀溶液样品的I(q)曲线进行拟合得到的回转半径（radius of gyration）随升降温过程的变化关系。
3. "fig_1b.csv": 记录了23 mol%甘油-水体系中浓度为200 mg/ml的溶菌酶样品，在降温过程中不同温度下测得的小角散射强度I(Q)随动量转移Q的变化关系，数据已扣除纯溶剂的散射本底。注：I(Q)单位为任意单位。
4. "fig_2a.csv": 记录了23 mol%甘油-水体系中浓度为200 mg/ml的溶菌酶样品，在降温过程中不同温度下测得的宽角散射强度I(Q)随动量转移Q的变化关系。注：I(Q)单位为任意单位。
5. "fig_2b.csv": 记录了23 mol%甘油-水体系中浓度为200 mg/ml的溶菌酶样品，在升温过程中不同温度下测得的宽角散射强度I(Q)随动量转移Q的变化关系。注：I(Q)单位为任意单位。
6. "fig_2c.csv": 加热过程中在T=197 K下测得的Q≈16~20 nm⁻¹附近的二维散射图案。
7. "fig_2d.csv": 加热过程中在T=245 K下测得的Q≈16~20 nm⁻¹附近的二维散射图案。
8. "fig_2e.csv": 降温过程中，中心位于Q≈17 nm⁻¹的冰Ih[002]衍射峰附近的I(Q)随温度的演化规律。
9. "fig_2f.csv": 升温过程中，中心位于Q≈17 nm⁻¹的冰Ih[002]衍射峰附近的I(Q)随温度的演化规律。
10. "fig_3a.csv": 浓度为200 mg/ml的溶菌酶甘油-水溶液，在降温至195 K的深温度循环过程中，小角X射线散射（Small-Angle X-ray Scattering, SAXS）的I(Q)峰位置对应的Q值随温度的变化关系。
11. "fig_3b.csv": 浓度为200 mg/ml的溶菌酶甘油-水溶液，在降温至225 K的中温循环过程中，小角X射线散射（SAXS）的I(Q)峰位置对应的Q值随温度的变化关系。
12. "fig_3c.csv": 浓度为200 mg/ml的溶菌酶甘油-水溶液，在降温至245 K的浅温度循环过程中，小角X射线散射（SAXS）的I(Q)峰位置对应的Q值随温度的变化关系。
13. "fig_3d.csv": 浓度为200 mg/ml的溶菌酶甘油-水溶液，在降温至195 K的深温度循环过程中，宽角X射线散射（Wide-Angle X-ray Scattering, WAXS）的I(Q)峰位置对应的Q值随温度的变化关系。
14. "fig_3e.csv": 浓度为200 mg/ml的溶菌酶甘油-水溶液，在降温至225 K的中温循环过程中，宽角X射线散射（WAXS）的I(Q)峰位置对应的Q值随温度的变化关系。
15. "fig_3f.csv": 浓度为200 mg/ml的溶菌酶甘油-水溶液，在降温至245 K的浅温度循环过程中，宽角X射线散射（WAXS）的I(Q)峰位置对应的Q值随温度的变化关系。
16. "fig_4a.csv": 采用双Yukawa模型（two-Yukawa model）拟合得到的，降温过程中不同温度（T=195~300 K）下的蛋白质-蛋白质结构因子S(Q)（structure factor S(Q)）。
17. "fig_4b.csv": 通过拟合小角散射曲线得到的吸引强度参数K₁（单位为k_B T，其中k_B为玻尔兹曼常数）随升降温过程的温度依赖关系。
18. "fig_4c.csv": 降温过程中不同温度（T=195~300 K）下的双Yukawa势函数。
19. "fig_4d.csv": 通过建模得到的结构因子推导得到的不同温度（T=195~300 K）下的径向分布函数g(r)（pair distribution function g(r)）。
此外，附带了Jupyter Notebook文件"open-data.ipynb"，该文档演示了如何在Python环境中加载并绘制这些CSV格式的数据文件。