Molecular profile of hidradenitis suppurativa

Hidradenitis Suppurativa molecular taxonomy and key signaling pathways were studied by whole transcriptome profiling. Dysregulated genes were detected by comparing lesional and non lesional skin obtained from female HS patients and matched healthy controls using the Agilent array platform Total RNA was obtained from full thickness skin specimens taken from both lesional and non lesional sites in 8 female patients diagnosed with Hurley stage II-III Hidradenitis Suppurativa, and from clear skin sites in 8 healthy controls