Multivariate logistic regression analysis of the miRNA prediction score modelling chemotherapy-resistance (defined as progression/relapse > 6 months, in the clinical cohort (n = 170).
This study was aimed to identify genes that alter resistance to pemetrexed, to elucidate the mechanism underlying resistance to pemetrexed in malignant pleural mesothelioma cell lines.
Tumor resistance to anti-cancer drugs is a major huddle in chemotherapy. To identify cancer genes that contribute to chemoresistance, B16 mouse melanoma cells were used as a model. We used microarrays