Prevalence of antibodies to equine alphaviruses in the State of Pará, Brazil

ABSTRACT: The State of Pará comprises 26% of Brazilian Amazon region, where a large diversity of arboviruses has been described. This study sought to assess the prevalence and distribution of hemagglutination inhibition (HI) antibodies against antigens of four alphaviruses (Togaviridae: Alphavirus ) from the species: Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), Mayaro virus (MAYV), and Mucambo virus (MUCV) in 753 serum samples of horses in Pará State, Brazil. All investigated arboviruses were detected and indicate that horses are susceptible to these alphaviruses, and show evidences of their active circulation in farm animals in the Brazilian Amazon.

摘要：帕拉州占巴西亚马逊地区的26%，该区域已被报道存在高度多样的虫媒病毒（arboviruses）。本研究旨在评估巴西帕拉州753份马血清样本中，针对4种隶属于披膜病毒科（Togaviridae）甲病毒属（Alphavirus）的甲病毒抗原的血凝抑制（hemagglutination inhibition, HI）抗体的流行率与分布特征，这4种病毒分别为东部马脑炎病毒（EEEV）、西部马脑炎病毒（WEEV）、马亚罗病毒（MAYV）以及穆坎博病毒（MUCV）。所有受试的4种虫媒病毒的抗体均被检出，结果表明马对这些甲病毒易感，并证实这些病毒在巴西亚马逊地区的养殖家畜中存在活跃的传播循环。