Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction. Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction

Bulk RNA-Sequencing of EHTs subjected to tachypacing to probe the mechanism of tachycardia-induced cardiac dysfunction. Overall design: EHTs were made from iPSC derived cardiomyocytes and matured. EHTs were paced at 3Hz for varying durations to probe the effect of tachycardia on cardiac transcriptome. *** Submitter states that missing raw files are due to patient privacy concerns. ***