Parameters of the CK model.

Shown are all model parameters describing the enzyme kinetics and transport across the mitochondrial outer membrane. The thirds column gives the parameter values obtained from the literature. If a standard measurement error could be obtained from literature, the value is given. We also give the parameter values after least-squares optimization to experiment data. We finally give means and standard deviations of the parameter ensemble. Note that the model parameters for maximum backwards velocity of both CK reactions, Vmax,Mi,b and Vmax,MM,b are not listed because their values are dynamically calculated from other parameter values via the Haldane relation: avalues which determine the spread of the prior distribution for parameters with standard errors not available from the experimental literature were set to 0.336, which is the maximum value for parameters where the standard error is known from the literature.