Oral Microbiota in Infants Fed a Formula Supplemented with Bovine Milk Fat Globule Membranes

The present study aimed to characterize the otal microbiota in infants fed with formula supplemented with MFGM, standard formula or human milk. The oral microbiota was analyzed at 4 (n=124) and 12 (n=166) months of age using Illumina MiSeq multiplex sequencing and taxonomic resolution against the HOMD 16S rDNA database of oral bacteria.

本研究旨在表征喂食添加乳脂球膜（Milk Fat Globule Membrane，MFGM）强化配方奶粉、标准配方奶粉或母乳的婴儿的口腔微生物群。本研究于婴儿4月龄（n=124）及12月龄（n=166）时，采用Illumina MiSeq多重测序技术，并以口腔细菌的人类口腔微生物组数据库（Human Oral Microbiome Database，HOMD）16S rDNA数据库作为参考进行分类学鉴定，对其口腔微生物群进行分析。