Role of oral antibiotics in reducing the chance of infection after operations for cancer of the rectum

Intervention1: Oral antibiotic bowel preparation: All the patients in this arm in addition to the bowel preparation solution ( 45 ml of Exelyte bowel preparation solution ( monobasic sodium phosphate dihydrate 24.417 g, disodium hydrogen orthophosphate dihydrate 5.439 g) to be consumed at 8 am and 4 pm ), will also receive 3 tablets each of, 1 gm of Erythromycin Estolate and 400 mg of Metronidazole in the package, to be taken at 1pm, 2pm and 11 pm, on the day prior to surgery
Control Intervention1: Mechanical Bowel preparation : Exelyte: 2 bottles of 45 ml of Exelyte bowel preparation solution ( monobasic sodium phosphate dihydrate 24.417 g, disodium hydrogen orthophosphate dihydrate 5.439 g) to be consumed at 8 am and 4 pm on the day prior to surgery.
Primary outcome(s): . To evaluate and assess the superiority of oral antibiotic bowel preparation in reducing incidence of surgical site infections in patients undergoing elective resection for rectal cancer in comparison to only mechanical bowel preparation at a tertiary care center in India.Timepoint: 30 days from the day of surgery
Study Design: Randomized, Parallel Group Trial
Method of generating randomization sequence:Computer generated randomization Method of allocation concealment:Sequentially numbered, sealed, opaque envelopes Blinding and masking:Outcome Assessor Blinded