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Catalyst-Free and Selective C–N Bond Functionalization: Stereospecific Three-Component Coupling of Amines, Dichloromethane, and >P(O)H Species Affording α‑Aminophosphorus Compounds

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NIAID Data Ecosystem2026-03-07 收录
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https://figshare.com/articles/dataset/Catalyst_Free_and_Selective_C_N_Bond_Functionalization_Stereospecific_Three_Component_Coupling_of_Amines_Dichloromethane_and_P_O_H_Species_Affording_Aminophosphorus_Compounds/2219674
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Catalyst-free and selective C–N bond functionalization has been achieved through three-component coupling of amines, dihalomethane, and >P­(O)H species. This reaction takes place stereospecifically with retention of configuration at phosphorus, which can produce various new optically active phosphorus analogues of α-amino acids.
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2015-01-02
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