Additional file 2 of A combined genome-wide association and molecular study of age-related hearing loss in H. sapiens

Additional file 2: Excel sheets with the lead SNPs that were associated with hearing difficulty, hearing aid use, speech-in-noise and tinnitus. Columns: CHR = chromosome, SNP = variant ids, either as rsID or in the format CHR_POSITION_ALLELE1_ALLELE2, BP = chromosomal position in basepairs (Genome Reference Consortium Human Build 37, GRCh37), P = P-value for association tests, P.GC_adjusted = P-values after adjusting for genomic inflation (this was only performed for tinnitus), SIGNIFICANT_ASSOCIATION = denotes whether a genome-wide association could be observed after adjusting for the family-wise error rate with Bonferroni-correction (P < 5*10-8), SNPS_IN_CLUMP (N) = the number of associated SNPs that were in linkage disequilibrium with the lead SNPs, CLUMP_COORDS = coordinates for the first and last associated SNPs that were clumped with the lead SNP, CLUMP_SIZE (bp) = the size of the clumped region in basepairs, GENES_IN_CLUMP = genes that were located within each clumped region.